Sheehan syndrome, also known as Simmonds' syndrome or
postpartum hypopituitarism or postpartum pituitary necrosis, is
hypopituitarism, caused by ischemic necrosis due to blood loss and hypovolemic
shock during and after childbirth. Pituitary damage unrelated to pregnancy is
called Simmonds' disease. In a study of 1034 symptomatic adults, Sheehan’s
syndrome was found to be the sixth most frequent etiology of growth hormone
deficiency, being responsible for 3.1% of cases.